Searchable abstracts of presentations at key conferences in endocrinology

ea0011p292 | Diabetes, metabolism and cardiovascular | ECE2006

Glucose metabolism, insulin secretion and insulin sensitivity in juvenile hemochromatosis

Angelopoulos N , Noutsou M , Goula A , Tolis G

Among specific diabetes subtypes secondary to pancreatopathies, hereditary hemochromatosis is an inherited disorder of iron metabolism, resulting to excessive iron overload and tissue damage in various organs. We report here the case of a man with the young-onset form of the disease and we describe his glycaemic status, before and during venesection therapy. A 25-year-old man attended our clinic in Athens, Greece, with hypogonadotropic hypogonadism due to hereditary hemochroma...

ea0011p6 | Bone | ECE2006

Circulating osteoprotegerin and receptor activator of NF- κB ligand system in patients with beta-thalassemia major

Angelopoulos N , Rombopoulos G , Kaltsas D , Kaltzidou V , Katounda E , Tolis G

Objectives: To characterize the possible role of the osteoprotegerin (OPG) and receptor activator of NF-κB ligand (RANKL) system in thalassemia-related bone loss.Background: Osteoporosis represents an important cause of morbidity in patients with β-thalassemia major and its aetiology is multifactorial.Methods: Serum concentrations of OPG, RANKL, markers of bone turnover and lumbar spine bone mineral density (BMD) were mea...